The Henry Samueli School of Engineering
University of California, Irvine
The Hui Lab is focused on leveraging microtechnology to understand and improve human health.
Spatial Cell Biology – How does the spatial organization of cells within tissue determine the emergent biological function? Our platforms allow dynamic manipulation of tissue organization during cell culture, enabling unconventional experiments and new insights into cell-cell interaction. We are engaged in problems such as tumor angiogenesis during cancer progression, and the determination of cellular fate in stem cell development.
Global Health Diagnostics – How can we bring hospital laboratory tests into the homes of families living in limited-resource settings? We are building computers that run on air pressure instead of electricity. We envision automated laboratories on a microchip that can be cheaply stamped out of plastic.
Dino Di Carlo
Professor and Graduate Vice Chair
Department of Bioengineering
University of California, Los Angeles
Complex biological organisms can be viewed as hierarchical ensembles of cooperating units with controlling elements that operate at the micro & nanoscale. In these systems, dysfunction at the fundamental cellular and molecular levels is responsible for a variety of diseases including cancer. Another hallmark of these systems is a dependence on microscale fluid vessels (e.g. capillaries, lymphatic vessels) for proper survival and function. Considering the similar scales and fluid environments, engineered micro- and nanofluidic devices appear ideally suited to diagnose, simulate, and probe biological systems.
We are exploiting unique physics, microenvironment control, and the potential for automation associated with miniaturized systems for applications in basic biology, medical diagnostics, and cellular engineering.
Engineering Science Building, Room 3231C
University of California, Santa Barbara
The research in the Pennathur Laboratory is focused on novel studies of chemical and biological species using fabricated micro- and nanoscale devices. The scope of the research program is broad, spanning the fields of Physics, Biology, Chemistry, and Engineering. The research goals are also broad, focusing on the fundamental science of nanoscale systems, while also exploring exciting technological possibilities. Major efforts include, general electrokinetics, creating and developing enabling micro- and nanofluidic tools to identify and characterize chemical and biological compounds, improving current bionalaytical devices, and designing/engineering entire systems for point-of-care usage.
Erkin Seker, University of California, Davis
Anderson Shum, Hong Kong University
David Wood, University of Minnesota
Jackie Linnes, Purdue University
Wei Gao, California Institute of Technology
Hirofumi Shintaku, Kyoto University
Angela Wu, Hong Kong University of Science and Technology
Kamlesh Patel, Sandia National Labs
Hugh Lee, Purdue University
Manasi Raje, TL Biolabs
Daniel Sipes, The Genomics Institute of the Novartis Research Foundation
Dwayne Vickers, The Genomics Institute of the Novartis Research Foundation
Timothy Dawes, Genentech